https://www.theguardian.com/world/20...d-cold-vaccineA universal coronavirus vaccine would need to trigger antibodies that recognise and neutralise a range of coronaviruses, scientists said, stopping the virus from entering hosts cells and replicating.
In the new study, the researchers investigated whether antibodies targeting the “S2 subunit” of Sars-CoV-2’s spike protein also neutralise other coronaviruses. The researchers found that after vaccinating mice with Sars-CoV-2 S2, the mice created antibodies able to neutralise a number of other animal and human coronaviruses.
They included the common cold coronavirus HCoV-OC43, the original strain of Sars-CoV-2, the D614G mutant that dominated in the first wave, Alpha, Beta, Delta, the original Omicron and two bat coronaviruses. The findings are published in the journal Science Translational Medicine.